Varaico: Literature-Extracted Genetic Variants

Gene:CCNB1
Variant:p.H280Y

CCNB1

211 papers

RefSeq Summary

The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). The encoded protein is necessary ...

Pfam Domains

Cyclin_Naa 173–298UCSCCyclin, N-terminal domain
Cyclin_Caa 300–418UCSCCyclin, C-terminal domain

Gene Aliases

HGNC Name

cyclin B1

HGNC Alias Name

G2/mitotic-specific cyclin B1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_031966.4
p.H280Y
c.838C>T
Surrounding Variants
1 paper
NM_031966.4
p.H280N
c.838C>A
1 paper
NM_031966.4
p.H280R
c.839A>G
1 paper
NM_031966.4
p.K279K
c.837G>A
1 paper
NM_031966.4
p.K279R
c.836A>G
1 paper
NM_031966.4
p.H280H
c.840C>T
1 paper
NM_031966.4
p.K279E
c.835A>G
1 paper
NM_031966.4
p.Q281*
c.841C>T
1 paper
NM_031966.4
p.Q281R
c.842A>G
1 paper
NM_031966.4
p.T278T
c.834T>C
1 paper
NM_031966.4
p.Q281Q
c.843A>G
1 paper
NM_031966.4
p.T278I
c.833C>T
1 paper
NM_031966.4
p.T278A
c.832A>G
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