Varaico: Literature-Extracted Genetic Variants

Gene:CCNB1
Variant:p.M285T

CCNB1

211 papers

RefSeq Summary

The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). The encoded protein is necessary ...

Pfam Domains

Cyclin_Naa 173–298UCSCCyclin, N-terminal domain
Cyclin_Caa 300–418UCSCCyclin, C-terminal domain

Gene Aliases

HGNC Name

cyclin B1

HGNC Alias Name

G2/mitotic-specific cyclin B1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_031966.4
p.M285T
c.854T>C
Surrounding Variants
1 paper
NM_031966.4
p.M285I
c.855G>A
1 paper
NM_031966.4
p.M285I
c.855G>C
1 paper
NM_031966.4
p.M285I
c.855G>T
1 paper
NM_031966.4
p.Q284Q
c.852G>A
1 paper
NM_031966.4
p.E286K
c.856G>A
1 paper
NM_031966.4
p.E286A
c.857A>C
1 paper
NM_031966.4
p.E286G
c.857A>G
1 paper
NM_031966.4
p.E286E
c.858A>G
1 paper
NM_031966.4
p.Q284*
c.850C>T
1 paper
NM_031966.4
p.R283R
c.849A>G
1 paper
NM_031966.4
p.M287V
c.859A>G
1 paper
NM_031966.4
p.R283K
c.848G>A
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