Varaico: Literature-Extracted Genetic Variants

Gene:CD2
Variant:p.M1I

CD2

394 papers

RefSeq Summary

The protein encoded by this gene is a surface antigen found on all peripheral blood T-cells. The encoded protein interacts with LFA3 (CD58) on antigen presenting cells to optimize immune recognition. ...

Pfam Domains

V-setaa 28–127UCSCImmunoglobulin V-set domain
C2-setaa 135–205UCSCImmunoglobulin C2-set domain

Gene Aliases

HGNC Name

CD2 molecule

HGNC Previous Symbol

SRBC

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_001767.5
p.M1I
c.3G>A
Surrounding Variants
1 paper
NM_001767.5
p.M1I
c.3G>C
1 paper
NM_001767.5
p.M1I
c.3G>T
1 paper
NM_001767.5
p.S2G
c.4A>G
1 paper
NM_001767.5
p.M1K
c.2T>A
1 paper
NM_001767.5
p.M1T
c.2T>C
1 paper
NM_001767.5
p.S2delFs
c.6delC
1 paper
NM_001767.5
p.F3insFs
c.8_9insT
1 paper
NM_001767.5
p.F3_P4insFs
c.9_10insA
1 paper
NM_001767.5
p.P4P
c.12A>C
1 paper
NM_001767.5
p.P4P
c.12A>G
1 paper
NM_001767.5
p.P4P
c.12A>T
1 paper
NM_001767.5
p.C5_L12delFs
c.15_36del22
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."