Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 850 variants

11 papers

NM_014143.4

p.A157T

c.469G>A

10 papers

NM_014143.4

p.A5P

c.13G>C

7 papers

NM_014143.4

p.P146R

c.437C>G

6 papers

NM_014143.4

p.E152*

c.454G>T

4 papers

NM_014143.4

p.N17D

c.49A>G

4 papers

NM_014143.4

p.A18T

c.52G>A

4 papers

NM_014143.4

p.A18S

c.52G>T

4 papers

NM_014143.4

p.D49V

c.146A>T

4 papers

NM_014143.4

p.D61V

c.182A>T

4 papers

NM_014143.4

p.V104L

c.310G>C

4 papers

NM_014143.4

p.E152Q

c.454G>C

4 papers

NM_014143.4

p.A232V

c.695C>T