Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.I3M

c.9A>G

Surrounding Variants

1 paper

NM_014143.4

p.I3I

c.9A>T

1 paper

NM_014143.4

p.F4delins

c.10delinsT

1 paper

NM_014143.4

p.F4fs

c.10_11fs

1 paper

NM_014143.4

p.I3V

c.7A>G

1 paper

NM_014143.4

p.F4S

c.11T>C

1 paper

NM_014143.4

p.R2R

c.6G>A

3 papers

NM_014143.4

p.A5T

c.13G>A

10 papers

NM_014143.4

p.A5P

c.13G>C

1 paper

NM_014143.4

p.A5D

c.14C>A

3 papers

NM_014143.4

p.M1I

c.3G>A

2 papers

NM_014143.4

p.M1I

c.3G>C

1 paper

NM_014143.4

p.M1_R2insFs

c.3_4insA