Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.F7Y

c.20T>A

Surrounding Variants

1 paper

NM_014143.4

p.F7fs

c.19_20fs

1 paper

NM_014143.4

p.I8L

c.22A>C

1 paper

NM_014143.4

p.I8V

c.22A>G

2 papers

NM_014143.4

p.I8L

c.22A>T

1 paper

NM_014143.4

p.V6V

c.18C>T

1 paper

NM_014143.4

p.I8K

c.23T>A

1 paper

NM_014143.4

p.V6A

c.17T>C

2 papers

NM_014143.4

p.I8M

c.24A>G

2 papers

NM_014143.4

p.I8I

c.24A>T

1 paper

NM_014143.4

p.V6I

c.16G>A

1 paper

NM_014143.4

p.V6L

c.16G>C

1 paper

NM_014143.4

p.A5A

c.15T>G