Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.W13C

c.39G>T

Surrounding Variants

2 papers

NM_014143.4

p.W13*

c.39G>A

1 paper

NM_014143.4

p.W13C

c.39G>C

1 paper

NM_014143.4

p.H14Y

c.40C>T

2 papers

NM_014143.4

p.W13*

c.38G>A

1 paper

NM_014143.4

p.W13S

c.38G>C

1 paper

NM_014143.4

p.H14R

c.41A>G

1 paper

NM_014143.4

p.W13delFs

c.39delG

1 paper

NM_014143.4

p.Y12F

c.35A>T

1 paper

NM_014143.4

p.L15L

c.43T>C

1 paper

NM_014143.4

p.L15fs

c.43_44fs

1 paper

NM_014143.4

p.L15fs

c.43_44fs

1 paper

NM_014143.4

p.T11T

c.33C>T