Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.N17N

c.51C>T

Surrounding Variants

1 paper

NM_014143.4

p.N17S

c.50A>G

1 paper

NM_014143.4

p.N17I

c.50A>T

4 papers

NM_014143.4

p.A18T

c.52G>A

2 papers

NM_014143.4

p.A18P

c.52G>C

4 papers

NM_014143.4

p.A18S

c.52G>T

1 paper

NM_014143.4

p.N17H

c.49A>C

4 papers

NM_014143.4

p.N17D

c.49A>G

1 paper

NM_014143.4

p.A18G

c.53C>G

1 paper

NM_014143.4

p.A18V

c.53C>T

1 paper

NM_014143.4

p.L16P

c.47T>C

1 paper

NM_014143.4

p.L16R

c.47T>G

1 paper

NM_014143.4

p.L16M

c.46C>A