Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_014143.4

p.K25E

c.73A>G

Surrounding Variants

1 paper

NM_014143.4

p.K25Q

c.73A>C

1 paper

NM_014143.4

p.K25R

c.74A>G

1 paper

NM_014143.4

p.K25M

c.74A>T

3 papers

NM_014143.4

p.P24L

c.71C>T

1 paper

NM_014143.4

p.P24delins

c.71_72delinsTT

1 paper

NM_014143.4

p.K25N

c.75G>C

2 papers

NM_014143.4

p.K25N

c.75G>T

2 papers

NM_014143.4

p.P24S

c.70C>T

1 paper

NM_014143.4

p.D26N

c.76G>A

1 paper

NM_014143.4

p.D26Y

c.76G>T

3 papers

NM_014143.4

p.D26G

c.77A>G

1 paper

NM_014143.4

p.D26D

c.78C>T