Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.Y28_V29insFs

c.84_85insC

Surrounding Variants

1 paper

NM_014143.4

p.Y28S

c.83A>C

2 papers

NM_014143.4

p.Y28F

c.83A>T

2 papers

NM_014143.4

p.V29M

c.85G>A

1 paper

NM_014143.4

p.V29insFs

c.86dupT

1 paper

NM_014143.4

p.Y28H

c.82T>C

1 paper

NM_014143.4

p.V29G

c.86T>G

1 paper

NM_014143.4

p.L27I

c.79C>A

1 paper

NM_014143.4

p.V30E

c.89T>A

1 paper

NM_014143.4

p.V30A

c.89T>C

1 paper

NM_014143.4

p.D26D

c.78C>T

3 papers

NM_014143.4

p.D26G

c.77A>G

1 paper

NM_014143.4

p.E31K

c.91G>A