Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.E31A

c.92A>C

Surrounding Variants

1 paper

NM_014143.4

p.E31G

c.92A>G

2 papers

NM_014143.4

p.E31E

c.93G>A

1 paper

NM_014143.4

p.E31K

c.91G>A

1 paper

NM_014143.4

p.Y32H

c.94T>C

2 papers

NM_014143.4

p.Y32C

c.95A>G

1 paper

NM_014143.4

p.Y32F

c.95A>T

1 paper

NM_014143.4

p.V30E

c.89T>A

1 paper

NM_014143.4

p.V30A

c.89T>C

1 paper

NM_014143.4

p.G33C

c.97G>T

1 paper

NM_014143.4

p.V29G

c.86T>G

2 papers

NM_014143.4

p.V29M

c.85G>A

1 paper

NM_014143.4

p.V29insFs

c.86dupT