Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.N35T

c.104A>C

Surrounding Variants

1 paper

NM_014143.4

p.N35H

c.103A>C

1 paper

NM_014143.4

p.N35D

c.103A>G

1 paper

NM_014143.4

p.N35K

c.105T>A

1 paper

NM_014143.4

p.N35K

c.105T>G

1 paper

NM_014143.4

p.M36V

c.106A>G

1 paper

NM_014143.4

p.M36T

c.107T>C

1 paper

NM_014143.4

p.S34delFs

c.101delG

1 paper

NM_014143.4

p.M36I

c.108G>A

1 paper

NM_014143.4

p.M36I

c.108G>C

1 paper

NM_014143.4

p.M36I

c.108G>T

1 paper

NM_014143.4

p.I38_K41delFs

c.112_121del10

1 paper

NM_014143.4

p.T37K

c.110C>A