Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.E39D

c.117A>C

Surrounding Variants

1 paper

NM_014143.4

p.E39D

c.117A>T

1 paper

NM_014143.4

p.C40R

c.118T>C

1 paper

NM_014143.4

p.E39K

c.115G>A

1 paper

NM_014143.4

p.C40Y

c.119G>A

1 paper

NM_014143.4

p.E39Q

c.115G>C

1 paper

NM_014143.4

p.E39*

c.115G>T

1 paper

NM_014143.4

p.I38M

c.114T>G

1 paper

NM_014143.4

p.K41Fs

c.121delinsTTFs

2 papers

NM_014143.4

p.I38T

c.113T>C

1 paper

NM_014143.4

p.T37K

c.110C>A

1 paper

NM_014143.4

p.T37R

c.110C>G

1 paper

NM_014143.4

p.F42V

c.124T>G