Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.L48S

c.143T>C

Surrounding Variants

2 papers

NM_014143.4

p.D49N

c.145G>A

1 paper

NM_014143.4

p.D49H

c.145G>C

1 paper

NM_014143.4

p.Q47R

c.140A>G

1 paper

NM_014143.4

p.D49G

c.146A>G

4 papers

NM_014143.4

p.D49V

c.146A>T

1 paper

NM_014143.4

p.Q47E

c.139C>G

1 paper

NM_014143.4

p.L50M

c.148C>A

1 paper

NM_014143.4

p.L50V

c.148C>G

1 paper

NM_014143.4

p.K46R

c.137A>G

1 paper

NM_014143.4

p.L50P

c.149T>C

1 paper

NM_014143.4

p.K46Q

c.136A>C

1 paper

NM_014143.4

p.K46*

c.136A>T