Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.A51T

c.151G>A

Surrounding Variants

2 papers

NM_014143.4

p.A51S

c.151G>T

3 papers

NM_014143.4

p.A51D

c.152C>A

1 paper

NM_014143.4

p.A51G

c.152C>G

3 papers

NM_014143.4

p.A51V

c.152C>T

1 paper

NM_014143.4

p.L50L

c.150G>A

1 paper

NM_014143.4

p.A51A

c.153T>A

1 paper

NM_014143.4

p.L50P

c.149T>C

1 paper

NM_014143.4

p.L50M

c.148C>A

1 paper

NM_014143.4

p.L50V

c.148C>G

1 paper

NM_014143.4

p.A52S

c.154G>T

3 papers

NM_014143.4

p.A52V

c.155C>T

1 paper

NM_014143.4

p.L53del1

c.157_158delCTA