Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_014143.4

p.W57*

c.171G>A

Surrounding Variants

3 papers

NM_014143.4

p.W57*

c.170G>A

1 paper

NM_014143.4

p.E58K

c.172G>A

2 papers

NM_014143.4

p.W57S

c.170G>C

1 paper

NM_014143.4

p.W57L

c.170G>T

1 paper

NM_014143.4

p.E58G

c.173A>G

1 paper

NM_014143.4

p.W57G

c.169T>G

1 paper

NM_014143.4

p.Y56C

c.167A>G

1 paper

NM_014143.4

p.M59T

c.176T>C

1 paper

NM_014143.4

p.M59I

c.177G>A

1 paper

NM_014143.4

p.M59I

c.177G>C

1 paper

NM_014143.4

p.M59I

c.177G>T

2 papers

NM_014143.4

p.E60K

c.178G>A