Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_014143.4

p.D61V

c.182A>T

Surrounding Variants

2 papers

NM_014143.4

p.D61G

c.182A>G

1 paper

NM_014143.4

p.D61N

c.181G>A

1 paper

NM_014143.4

p.D61H

c.181G>C

1 paper

NM_014143.4

p.D61Y

c.181G>T

1 paper

NM_014143.4

p.D61E

c.183T>A

1 paper

NM_014143.4

p.D61E

c.183T>G

1 paper

NM_014143.4

p.E60A

c.179A>C

1 paper

NM_014143.4

p.K62delFs

c.186delG

2 papers

NM_014143.4

p.E60K

c.178G>A

1 paper

NM_014143.4

p.E60Q

c.178G>C

1 paper

NM_014143.4

p.K62N

c.186G>C

1 paper

NM_014143.4

p.K62N

c.186G>T