Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.N63Y

c.187A>T

Surrounding Variants

1 paper

NM_014143.4

p.K62N

c.186G>C

1 paper

NM_014143.4

p.K62N

c.186G>T

1 paper

NM_014143.4

p.K62delFs

c.186delG

1 paper

NM_014143.4

p.I64V

c.190A>G

1 paper

NM_014143.4

p.D61E

c.183T>A

1 paper

NM_014143.4

p.I64T

c.191T>C

1 paper

NM_014143.4

p.D61E

c.183T>G

2 papers

NM_014143.4

p.D61G

c.182A>G

4 papers

NM_014143.4

p.D61V

c.182A>T

1 paper

NM_014143.4

p.I64M

c.192T>G

1 paper

NM_014143.4

p.I65_Q66del2

c.193_197del6

1 paper

NM_014143.4

p.I65L

c.193A>C