Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.V68M

c.202G>A

Surrounding Variants

1 paper

NM_014143.4

p.V68E

c.203T>A

1 paper

NM_014143.4

p.V68A

c.203T>C

1 paper

NM_014143.4

p.F67C

c.200T>G

2 papers

NM_014143.4

p.H69N

c.205C>A

1 paper

NM_014143.4

p.H69Y

c.205C>T

1 paper

NM_014143.4

p.F67I

c.199T>A

1 paper

NM_014143.4

p.H69R

c.206A>G

1 paper

NM_014143.4

p.H69L

c.206A>T

1 paper

NM_014143.4

p.Q66fs

c.196_197fs

1 paper

NM_014143.4

p.Q66E

c.196C>G

1 paper

NM_014143.4

p.Q66*

c.196C>T

1 paper

NM_014143.4

p.G70R

c.208G>A