Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.H78Y

c.232C>T

Surrounding Variants

1 paper

NM_014143.4

p.H78R

c.233A>G

1 paper

NM_014143.4

p.Q77Q

c.231G>A

1 paper

NM_014143.4

p.Q77H

c.231G>C

1 paper

NM_014143.4

p.S79G

c.235A>G

1 paper

NM_014143.4

p.Q77E

c.229C>G

1 paper

NM_014143.4

p.S79N

c.236G>A

1 paper

NM_014143.4

p.S79insFs

c.237dupT

1 paper

NM_014143.4

p.V76A

c.227T>C

1 paper

NM_014143.4

p.S80R

c.238A>C

1 paper

NM_014143.4

p.V76I

c.226G>A

1 paper

NM_014143.4

p.V76L

c.226G>C

1 paper

NM_014143.4

p.V76F

c.226G>T