Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.R86Q

c.257G>A

Surrounding Variants

1 paper

NM_014143.4

p.R86P

c.257G>C

2 papers

NM_014143.4

p.R86W

c.256C>T

1 paper

NM_014143.4

p.A85A

c.255C>T

1 paper

NM_014143.4

p.A85V

c.254C>T

2 papers

NM_014143.4

p.L87L

c.261G>A

1 paper

NM_014143.4

p.A85T

c.253G>A

1 paper

NM_014143.4

p.A85fs

c.253_254fs

1 paper

NM_014143.4

p.A85S

c.253G>T

1 paper

NM_014143.4

p.R84S

c.252G>C

1 paper

NM_014143.4

p.L88M

c.262T>A

1 paper

NM_014143.4

p.L88V

c.262T>G

1 paper

NM_014143.4

p.L88fs

c.262_263fs