Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.K89N

c.267G>T

Surrounding Variants

1 paper

NM_014143.4

p.K89K

c.267G>A

1 paper

NM_014143.4

p.K89N

c.267G>C

1 paper

NM_014143.4

p.K89R

c.266A>G

1 paper

NM_014143.4

p.D90fs

c.268_269fs

1 paper

NM_014143.4

p.D90Y

c.268G>T

1 paper

NM_014143.4

p.D90A

c.269A>C

1 paper

NM_014143.4

p.K89E

c.265A>G

1 paper

NM_014143.4

p.D90V

c.269A>T

1 paper

NM_014143.4

p.D90E

c.270C>A

1 paper

NM_014143.4

p.D90E

c.270C>G

2 papers

NM_014143.4

p.L88L

c.264G>A

1 paper

NM_014143.4

p.L88F

c.264G>C