Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.S93S

c.279C>G

Surrounding Variants

2 papers

NM_014143.4

p.G95R

c.283G>A

2 papers

NM_014143.4

p.G95R

c.283G>C

2 papers

NM_014143.4

p.L92F

c.274C>T

1 paper

NM_014143.4

p.G95E

c.284G>A

1 paper

NM_014143.4

p.Q91H

c.273G>C

1 paper

NM_014143.4

p.Q91H

c.273G>T

1 paper

NM_014143.4

p.N96H

c.286A>C

1 paper

NM_014143.4

p.Q91R

c.272A>G

1 paper

NM_014143.4

p.N96Y

c.286A>T

1 paper

NM_014143.4

p.N96S

c.287A>G

1 paper

NM_014143.4

p.Q91E

c.271C>G

1 paper

NM_014143.4

p.D90E

c.270C>A