Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.N96S

c.287A>G

Surrounding Variants

1 paper

NM_014143.4

p.N96H

c.286A>C

1 paper

NM_014143.4

p.N96Y

c.286A>T

1 paper

NM_014143.4

p.N96K

c.288T>A

1 paper

NM_014143.4

p.A97T

c.289G>A

1 paper

NM_014143.4

p.A97P

c.289G>C

1 paper

NM_014143.4

p.A97D

c.290C>A

1 paper

NM_014143.4

p.A97G

c.290C>G

2 papers

NM_014143.4

p.A97V

c.290C>T

1 paper

NM_014143.4

p.G95E

c.284G>A

2 papers

NM_014143.4

p.G95R

c.283G>A

2 papers

NM_014143.4

p.G95R

c.283G>C

2 papers

NM_014143.4

p.A98T

c.292G>A