Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.Q100H

c.300G>T

Surrounding Variants

1 paper

NM_014143.4

p.Q100H

c.300G>C

1 paper

NM_014143.4

p.Q100R

c.299A>G

1 paper

NM_014143.4

p.Q100L

c.299A>T

1 paper

NM_014143.4

p.Q100delFs

c.300delG

1 paper

NM_014143.4

p.I101T

c.302T>C

1 paper

NM_014143.4

p.T102I

c.305C>T

1 paper

NM_014143.4

p.D103_L106delFs

c.307_316del10

1 paper

NM_014143.4

p.A98V

c.293C>T

1 paper

NM_014143.4

p.D103N

c.307G>A

1 paper

NM_014143.4

p.D103H

c.307G>C

1 paper

NM_014143.4

p.D103Y

c.307G>T

1 paper

NM_014143.4

p.D103G

c.308A>G