Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.D108N

c.322G>A

Surrounding Variants

1 paper

NM_014143.4

p.Q107H

c.321G>C

1 paper

NM_014143.4

p.Q107K

c.319C>A

1 paper

NM_014143.4

p.Q107*

c.319C>T

1 paper

NM_014143.4

p.A109T

c.325G>A

1 paper

NM_014143.4

p.A109S

c.325G>T

1 paper

NM_014143.4

p.A109V

c.326C>T

1 paper

NM_014143.4

p.L106F

c.318G>C

1 paper

NM_014143.4

p.L106F

c.318G>T

2 papers

NM_014143.4

p.L106*

c.317T>A

2 papers

NM_014143.4

p.G110R

c.328G>A

2 papers

NM_014143.4

p.G110R

c.328G>C

1 paper

NM_014143.4

p.L106fs

c.316_317fs