Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.C114S

c.340T>A

Surrounding Variants

1 paper

NM_014143.4

p.R113R

c.339C>T

1 paper

NM_014143.4

p.C114Y

c.341G>A

1 paper

NM_014143.4

p.C114C

c.342C>T

2 papers

NM_014143.4

p.R113H

c.338G>A

1 paper

NM_014143.4

p.R113L

c.338G>T

1 paper

NM_014143.4

p.M115L

c.343A>C

1 paper

NM_014143.4

p.M115L

c.343A>T

1 paper

NM_014143.4

p.R113S

c.337C>A

1 paper

NM_014143.4

p.R113C

c.337C>T

1 paper

NM_014143.4

p.M115T

c.344T>C

2 papers

NM_014143.4

p.Y112C

c.335A>G

1 paper

NM_014143.4

p.I116V

c.346A>G