Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.Y118C

c.353A>G

Surrounding Variants

1 paper

NM_014143.4

p.Y118F

c.353A>T

1 paper

NM_014143.4

p.G119S

c.355G>A

1 paper

NM_014143.4

p.G119R

c.355G>C

1 paper

NM_014143.4

p.G119_A121delFs

c.356_363del8

2 papers

NM_014143.4

p.G119D

c.356G>A

1 paper

NM_014143.4

p.S117T

c.350G>C

1 paper

NM_014143.4

p.G119V

c.356G>T

1 paper

NM_014143.4

p.I116M

c.348C>G

1 paper

NM_014143.4

p.I116I

c.348C>T

1 paper

NM_014143.4

p.G120fs

c.358_359fs

1 paper

NM_014143.4

p.I116V

c.346A>G

1 paper

NM_014143.4

p.G120G

c.360T>A