Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.N138K

c.414C>A

Surrounding Variants

1 paper

NM_014143.4

p.N138K

c.414C>G

1 paper

NM_014143.4

p.N138T

c.413A>C

1 paper

NM_014143.4

p.Q139E

c.415C>G

1 paper

NM_014143.4

p.N138H

c.412A>C

1 paper

NM_014143.4

p.N138D

c.412A>G

1 paper

NM_014143.4

p.Q139R

c.416A>G

1 paper

NM_014143.4

p.I137I

c.411C>T

1 paper

NM_014143.4

p.R140K

c.419G>A

3 papers

NM_014143.4

p.R140T

c.419G>C

2 papers

NM_014143.4

p.R140I

c.419G>T

1 paper

NM_014143.4

p.K136R

c.407A>G

1 paper

NM_014143.4

p.I141V

c.421A>G