Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.T148A

c.442A>G

Surrounding Variants

1 paper

NM_014143.4

p.V147A

c.440T>C

1 paper

NM_014143.4

p.V147I

c.439G>A

1 paper

NM_014143.4

p.S149A

c.445T>G

1 paper

NM_014143.4

p.S149Y

c.446C>A

7 papers

NM_014143.4

p.P146R

c.437C>G

1 paper

NM_014143.4

p.P146L

c.437C>T

1 paper

NM_014143.4

p.P146insFs

c.436_437insGG

1 paper

NM_014143.4

p.P146S

c.436C>T

1 paper

NM_014143.4

p.E150K

c.448G>A

1 paper

NM_014143.4

p.E150G

c.449A>G

1 paper

NM_014143.4

p.H151Y

c.451C>T

2 papers

NM_014143.4

p.H151R

c.452A>G