Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.L153P

c.458T>C

Surrounding Variants

1 paper

NM_014143.4

p.T154S

c.460A>T

1 paper

NM_014143.4

p.T154I

c.461C>T

1 paper

NM_014143.4

p.E152K

c.454G>A

4 papers

NM_014143.4

p.E152Q

c.454G>C

6 papers

NM_014143.4

p.E152*

c.454G>T

1 paper

NM_014143.4

p.C155S

c.463T>A

2 papers

NM_014143.4

p.H151R

c.452A>G

1 paper

NM_014143.4

p.H151L

c.452A>T

1 paper

NM_014143.4

p.C155S

c.464G>C

1 paper

NM_014143.4

p.H151Y

c.451C>T

1 paper

NM_014143.4

p.Q156K

c.466C>A

1 paper

NM_014143.4

p.Q156E

c.466C>G