Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.G159R

c.475G>C

Surrounding Variants

1 paper

NM_014143.4

p.G159S

c.475G>A

1 paper

NM_014143.4

p.G159C

c.475G>T

1 paper

NM_014143.4

p.G159D

c.476G>A

1 paper

NM_014143.4

p.E158G

c.473A>G

2 papers

NM_014143.4

p.E158V

c.473A>T

1 paper

NM_014143.4

p.E158K

c.472G>A

1 paper

NM_014143.4

p.E158Q

c.472G>C

1 paper

NM_014143.4

p.Y160H

c.478T>C

1 paper

NM_014143.4

p.P161T

c.481C>A

2 papers

NM_014143.4

p.P161S

c.481C>T

11 papers

NM_014143.4

p.A157T

c.469G>A

1 paper

NM_014143.4

p.A157S

c.469G>T