Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_014143.4

p.E164K

c.490G>A

Surrounding Variants

2 papers

NM_014143.4

p.E164Q

c.490G>C

2 papers

NM_014143.4

p.E164A

c.491A>C

1 paper

NM_014143.4

p.E164D

c.492A>C

1 paper

NM_014143.4

p.E164D

c.492A>T

1 paper

NM_014143.4

p.A163G

c.488C>G

1 paper

NM_014143.4

p.A163V

c.488C>T

1 paper

NM_014143.4

p.V165L

c.493G>C

1 paper

NM_014143.4

p.K162N

c.486G>C

1 paper

NM_014143.4

p.K162N

c.486G>T

1 paper

NM_014143.4

p.V165A

c.494T>C

3 papers

NM_014143.4

p.K162R

c.485A>G

2 papers

NM_014143.4

p.K162fs

c.484_485fs