Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.S169R

c.507C>G

Surrounding Variants

1 paper

NM_014143.4

p.S169R

c.507C>A

1 paper

NM_014143.4

p.S169N

c.506G>A

1 paper

NM_014143.4

p.S169R

c.505A>C

1 paper

NM_014143.4

p.S169C

c.505A>T

3 papers

NM_014143.4

p.D171N

c.511G>A

1 paper

NM_014143.4

p.T168A

c.502A>G

1 paper

NM_014143.4

p.D171G

c.512A>G

1 paper

NM_014143.4

p.W167C

c.501G>C

1 paper

NM_014143.4

p.W167C

c.501G>T

2 papers

NM_014143.4

p.H172Y

c.514C>T

1 paper

NM_014143.4

p.H172P

c.515A>C

1 paper

NM_014143.4

p.H172Q

c.516T>A