Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.V174L

c.520G>C

Surrounding Variants

2 papers

NM_014143.4

p.V174I

c.520G>A

1 paper

NM_014143.4

p.V174F

c.520G>T

1 paper

NM_014143.4

p.Q173H

c.519A>C

1 paper

NM_014143.4

p.Q173H

c.519A>T

1 paper

NM_014143.4

p.V174D

c.521T>A

1 paper

NM_014143.4

p.V174A

c.521T>C

1 paper

NM_014143.4

p.V174G

c.521T>G

1 paper

NM_014143.4

p.Q173E

c.517C>G

1 paper

NM_014143.4

p.H172Q

c.516T>A

1 paper

NM_014143.4

p.H172Q

c.516T>G

1 paper

NM_014143.4

p.S176delFs

c.526_527delAG

1 paper

NM_014143.4

p.H172P

c.515A>C