Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.L175L

c.525G>C

Surrounding Variants

1 paper

NM_014143.4

p.L175L

c.525G>A

1 paper

NM_014143.4

p.S176fs

c.526_527fs

1 paper

NM_014143.4

p.S176R

c.526A>C

1 paper

NM_014143.4

p.S176G

c.526A>G

1 paper

NM_014143.4

p.S176delFs

c.526_527delAG

2 papers

NM_014143.4

p.G177S

c.529G>A

1 paper

NM_014143.4

p.G177R

c.529G>C

1 paper

NM_014143.4

p.G177C

c.529G>T

1 paper

NM_014143.4

p.V174D

c.521T>A

1 paper

NM_014143.4

p.V174A

c.521T>C

1 paper

NM_014143.4

p.V174G

c.521T>G

2 papers

NM_014143.4

p.V174I

c.520G>A