Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.T181A

c.541A>G

Surrounding Variants

2 papers

NM_014143.4

p.T181I

c.542C>T

1 paper

NM_014143.4

p.T180T

c.540C>T

1 paper

NM_014143.4

p.T180I

c.539C>T

1 paper

NM_014143.4

p.T182P

c.544A>C

1 paper

NM_014143.4

p.T180A

c.538A>G

1 paper

NM_014143.4

p.T179I

c.536C>T

1 paper

NM_014143.4

p.N183H

c.547A>C

1 paper

NM_014143.4

p.N183D

c.547A>G

1 paper

NM_014143.4

p.N183S

c.548A>G

1 paper

NM_014143.4

p.K178R

c.533A>G

1 paper

NM_014143.4

p.K178E

c.532A>G

1 paper

NM_014143.4

p.S184P

c.550T>C