Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.E187K

c.559G>A

Surrounding Variants

2 papers

NM_014143.4

p.E187Q

c.559G>C

1 paper

NM_014143.4

p.E187*

c.559G>T

1 paper

NM_014143.4

p.E187V

c.560A>T

1 paper

NM_014143.4

p.R186T

c.557G>C

1 paper

NM_014143.4

p.E187D

c.561G>C

1 paper

NM_014143.4

p.E187D

c.561G>T

1 paper

NM_014143.4

p.R186G

c.556A>G

1 paper

NM_014143.4

p.E188K

c.562G>A

1 paper

NM_014143.4

p.E188Q

c.562G>C

1 paper

NM_014143.4

p.E188fs

c.562_563fs

1 paper

NM_014143.4

p.E188V

c.563A>T

1 paper

NM_014143.4

p.K185K

c.555G>A