Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.T194A

c.580A>G

Surrounding Variants

1 paper

NM_014143.4

p.S195R

c.583A>C

2 papers

NM_014143.4

p.V193M

c.577G>A

1 paper

NM_014143.4

p.S195N

c.584G>A

1 paper

NM_014143.4

p.S195I

c.584G>T

1 paper

NM_014143.4

p.N192K

c.576T>A

1 paper

NM_014143.4

p.N192K

c.576T>G

1 paper

NM_014143.4

p.N192I

c.575A>T

1 paper

NM_014143.4

p.S195R

c.585C>A

1 paper

NM_014143.4

p.S195R

c.585C>G

2 papers

NM_014143.4

p.T196P

c.586A>C

1 paper

NM_014143.4

p.T196A

c.586A>G

1 paper

NM_014143.4

p.F191L

c.573C>A