Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.T203S

c.607A>T

Surrounding Variants

1 paper

NM_014143.4

p.T203A

c.607A>G

1 paper

NM_014143.4

p.T202T

c.606A>G

1 paper

NM_014143.4

p.T203del1

c.607_608delACT

1 paper

NM_014143.4

p.T203N

c.608C>A

1 paper

NM_014143.4

p.T203S

c.608C>G

2 papers

NM_014143.4

p.T203I

c.608C>T

1 paper

NM_014143.4

p.T202R

c.605C>G

1 paper

NM_014143.4

p.T202I

c.605C>T

1 paper

NM_014143.4

p.N204I

c.611A>T

2 papers

NM_014143.4

p.T201I

c.602C>T

1 paper

NM_014143.4

p.N204K

c.612T>A

1 paper

NM_014143.4

p.N204K

c.612T>G