Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.F211L

c.633T>G

Surrounding Variants

1 paper

NM_014143.4

p.F211L

c.633T>A

2 papers

NM_014143.4

p.F211C

c.632T>G

1 paper

NM_014143.4

p.R212K

c.635G>A

1 paper

NM_014143.4

p.R212T

c.635G>C

1 paper

NM_014143.4

p.F211I

c.631T>A

1 paper

NM_014143.4

p.F211L

c.631T>C

1 paper

NM_014143.4

p.F211fs

c.631_632fs

1 paper

NM_014143.4

p.R213*

c.637A>T

1 paper

NM_014143.4

p.T210S

c.629C>G

1 paper

NM_014143.4

p.T210S

c.628A>T

1 paper

NM_014143.4

p.R213K

c.638G>A

1 paper

NM_014143.4

p.L214delFs

c.641delT