Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.P230S

c.688C>T

Surrounding Variants

1 paper

NM_014143.4

p.P230T

c.688C>A

1 paper

NM_014143.4

p.L229L

c.687A>G

1 paper

NM_014143.4

p.P230L

c.689C>T

1 paper

NM_014143.4

p.L229P

c.686T>C

1 paper

NM_014143.4

p.L231M

c.691C>A

2 papers

NM_014143.4

p.L231V

c.691C>G

1 paper

NM_014143.4

p.A232T

c.694G>A

1 paper

NM_014143.4

p.A232P

c.694G>C

1 paper

NM_014143.4

p.A232S

c.694G>T

1 paper

NM_014143.4

p.A232G

c.695C>G

4 papers

NM_014143.4

p.A232V

c.695C>T

1 paper

NM_014143.4

p.H233Y

c.697C>T