Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.I243V

c.727A>G

Surrounding Variants

2 papers

NM_014143.4

p.I243T

c.728T>C

1 paper

NM_014143.4

p.V242E

c.725T>A

1 paper

NM_014143.4

p.V242A

c.725T>C

1 paper

NM_014143.4

p.L244M

c.730C>A

1 paper

NM_014143.4

p.L244V

c.730C>G

1 paper

NM_014143.4

p.V242I

c.724G>A

1 paper

NM_014143.4

p.V242L

c.724G>T

1 paper

NM_014143.4

p.L241F

c.723G>C

1 paper

NM_014143.4

p.L241F

c.723G>T

1 paper

NM_014143.4

p.L244P

c.731T>C

1 paper

NM_014143.4

p.G245R

c.733G>A

1 paper

NM_014143.4

p.G245R

c.733G>C