Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

3 papers

NM_014143.4

p.G245V

c.734G>T

Surrounding Variants

1 paper

NM_014143.4

p.G245E

c.734G>A

1 paper

NM_014143.4

p.G245A

c.734G>C

1 paper

NM_014143.4

p.G245R

c.733G>A

1 paper

NM_014143.4

p.G245R

c.733G>C

3 papers

NM_014143.4

p.A246T

c.736G>A

1 paper

NM_014143.4

p.A246D

c.737C>A

1 paper

NM_014143.4

p.A246V

c.737C>T

1 paper

NM_014143.4

p.L244P

c.731T>C

1 paper

NM_014143.4

p.L244M

c.730C>A

1 paper

NM_014143.4

p.L244V

c.730C>G

2 papers

NM_014143.4

p.A246A

c.738C>T

2 papers

NM_014143.4

p.I243T

c.728T>C