Varaico: Literature-Extracted Genetic Variants

CD274

574 papers

RefSeq Summary

This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein...

Pfam Domains

V-setaa 22–132UCSCImmunoglobulin V-set domain

C2-set_2aa 135–220UCSCCD80-like C2-set immunoglobulin domain

Gene Aliases

HGNC Name

CD274 molecule

HGNC Previous Symbol

PDCD1LG1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_014143.4

p.G252C

c.754G>T

Surrounding Variants

2 papers

NM_014143.4

p.G252S

c.754G>A

1 paper

NM_014143.4

p.G252D

c.755G>A

1 paper

NM_014143.4

p.L251F

c.751C>T

1 paper

NM_014143.4

p.V253I

c.757G>A

1 paper

NM_014143.4

p.V253G

c.758T>G

2 papers

NM_014143.4

p.C250Y

c.749G>A

1 paper

NM_014143.4

p.C250F

c.749G>T

1 paper

NM_014143.4

p.C250G

c.748T>G

1 paper

NM_014143.4

p.A254G

c.761C>G

1 paper

NM_014143.4

p.L249S

c.746T>C

2 papers

NM_014143.4

p.L255M

c.763C>A

1 paper

NM_014143.4

p.L255V

c.763C>G