Varaico: Literature-Extracted Genetic Variants

Gene:CD28
Variant:p.Q74R

CD28

309 papers

RefSeq Summary

The protein encoded by this gene is essential for T-cell proliferation and survival, cytokine production, and T-helper type-2 development. Several alternatively spliced transcript variants encoding di...

Pfam Domains

V-set_2aa 23–142UCSCICOS V-set domain

Gene Aliases

HGNC Name

CD28 molecule

HGNC Previous Name

CD28 antigen (Tp44)

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_006139.4
p.Q74R
c.221A>G
Surrounding Variants
1 paper
NM_006139.4
p.Q74H
c.222G>C
1 paper
NM_006139.4
p.Q75*
c.223C>T
1 paper
NM_006139.4
p.Q77P
c.230A>C
2 papers
NM_006139.4
p.V78A
c.233T>C
1 paper
NM_006139.4
p.Y69C
c.206A>G
1 paper
NM_006139.4
p.Y79F
c.236A>T
1 paper
NM_006139.4
p.S80_T82ins1
c.239_244dup6
1 paper
NM_006139.4
p.S80*
c.239C>A
1 paper
NM_006139.4
p.S80*
c.239C>G
1 paper
NM_006139.4
p.S80delFs
c.240delA
1 paper
NM_006139.4
p.V65L
c.193G>C
1 paper
NM_006139.4
p.V65F
c.193G>T
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