Varaico: Literature-Extracted Genetic Variants

CD3D

76 papers

RefSeq Summary

The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the...

Pfam Domains

Ig_4aa 30–99UCSCT-cell surface glycoprotein CD3 delta chain

ITAMaa 146–165UCSCImmunoreceptor tyrosine-based activation motif

Gene Aliases

HGNC Name

CD3 delta subunit of T-cell receptor complex

HGNC Previous Symbol

T3D

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_000732.6

p.Q140K

c.418C>A

Surrounding Variants

4 papers

NM_000732.6

p.Q147R

c.440A>G

1 paper

NM_000732.6

p.Y149F

c.446A>T

1 paper

NM_000732.6

p.R153Q

c.458G>A

1 paper

NM_000732.6

p.G135R

c.403G>C

1 paper

NM_000732.6

p.G135R

c.403G>A

1 paper

NM_000732.6

p.E129G

c.386A>G

1 paper

NM_000732.6

p.G106C

c.316G>T

1 paper

NM_000732.6

p.A105S

c.313G>T

2 papers

NM_000732.6

p.V104M

c.310G>A

1 paper

NM_000732.6

p.P101S

c.301C>T

4 papers

NM_000732.6

p.C93*

c.279C>A

1 paper

NM_000732.6

p.C93R

c.277T>C