Varaico: Literature-Extracted Genetic Variants

CD4

453 papers

RefSeq Summary

This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presen...

Pfam Domains

igaa 27–122UCSCImmunoglobulin domain

C2-setaa 125–203UCSCImmunoglobulin C2-set domain

CD4-extracelaa 206–316UCSCCD4, extracellular

C2-setaa 317–390UCSCImmunoglobulin C2-set domain

Tcell_CD4_Caa 402–449UCSCT cell CD4 receptor C terminal region

Gene Aliases

HGNC Name

CD4 molecule

HGNC Alias Symbols

T4; Leu-3

Papers

RefSeq ID

Protein change

DNA change

1–12 of 234 variants

7 papers

NM_000616.5

p.R265W

c.793C>T

5 papers

NM_000616.5

p.Q24L

c.71A>T

4 papers

NM_000616.5

p.Q290*

c.868C>T

4 papers

NM_000616.5

p.S375W

c.1124C>G

4 papers

NM_000616.5

p.R426_R427Splc

c.1278+1G>A

3 papers

NM_000616.5

p.V386Splc

c.1157-1G>A

3 papers

NM_000616.5

p.H449Splc

c.1346+2T>C

2 papers

NM_000616.5

p.M1V

c.1A>G

2 papers

NM_000616.5

p.M1I

c.3G>A

2 papers

NM_000616.5

p.L10V

c.28T>G

2 papers

NM_000616.5

p.K33R

c.98A>G

2 papers

NM_000616.5

p.S56S

c.168C>A