Varaico: Literature-Extracted Genetic Variants

CD4

453 papers

RefSeq Summary

This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presen...

Pfam Domains

igaa 27–122UCSCImmunoglobulin domain

C2-setaa 125–203UCSCImmunoglobulin C2-set domain

CD4-extracelaa 206–316UCSCCD4, extracellular

C2-setaa 317–390UCSCImmunoglobulin C2-set domain

Tcell_CD4_Caa 402–449UCSCT cell CD4 receptor C terminal region

Gene Aliases

HGNC Name

CD4 molecule

HGNC Alias Symbols

T4; Leu-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000616.5

p.V5A

c.14T>C

Surrounding Variants

1 paper

NM_000616.5

p.P6A

c.16C>G

1 paper

NM_000616.5

p.P6delFs

c.18delT

1 paper

NM_000616.5

p.G4E

c.11G>A

1 paper

NM_000616.5

p.R3R

c.9G>A

1 paper

NM_000616.5

p.F7L

c.21T>A

1 paper

NM_000616.5

p.N2Y

c.4A>T

2 papers

NM_000616.5

p.M1I

c.3G>A

1 paper

NM_000616.5

p.M1T

c.2T>C

1 paper

NM_000616.5

p.M1insFs

c.2dupT

1 paper

NM_000616.5

p.M1L

c.1A>C

2 papers

NM_000616.5

p.M1V

c.1A>G

1 paper

NM_000616.5

p.M1L

c.1A>T