Varaico: Literature-Extracted Genetic Variants

CD4

453 papers

RefSeq Summary

This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presen...

Pfam Domains

igaa 27–122UCSCImmunoglobulin domain

C2-setaa 125–203UCSCImmunoglobulin C2-set domain

CD4-extracelaa 206–316UCSCCD4, extracellular

C2-setaa 317–390UCSCImmunoglobulin C2-set domain

Tcell_CD4_Caa 402–449UCSCT cell CD4 receptor C terminal region

Gene Aliases

HGNC Name

CD4 molecule

HGNC Alias Symbols

T4; Leu-3

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000616.5

p.L12_Q15delFs

c.35_44del10

Surrounding Variants

1 paper

NM_000616.5

p.L12L

c.34C>T

1 paper

NM_000616.5

p.V13M

c.37G>A

1 paper

NM_000616.5

p.L10F

c.30G>C

1 paper

NM_000616.5

p.L10F

c.30G>T

1 paper

NM_000616.5

p.V13A

c.38T>C

2 papers

NM_000616.5

p.L10V

c.28T>G

1 paper

NM_000616.5

p.L14P

c.41T>C

1 paper

NM_000616.5

p.L14insFs

c.42dupG

1 paper

NM_000616.5

p.F7L

c.21T>A

1 paper

NM_000616.5

p.A17T

c.49G>A

1 paper

NM_000616.5

p.A17V

c.50C>T

1 paper

NM_000616.5

p.P6delFs

c.18delT